To unlock the Challenges of Layton:
The Time Traveler's House : Complete the game
The Storyteller's House : Complete the three picture books
The Hotelier's House : Complete ten races model cars
The Messenger's House : Complete all 12 quests packages delivered by birds
To unlock the character profiles:
Get picarats 4200
To unlock artwork:
Get picarats 4500
To unlock the game's music:
Get picarats 4700
To unlock the characters' voices:
Get picarats 5000
To unlock the profiles of secondary characters:
Solve 168 puzzles
To unlock the cutscenes:
Get picarats 5200